023 Efficacy and tolerability of biologic therapies for psoriasis: network meta-analysis
نویسندگان
چکیده
منابع مشابه
Clinical efficacy of local injection therapies for lateral epicondylitis: A systematic review and network meta-analysis
Background: We aimed to compare the efficacy of local injection therapies for lateral epicondylitis in a Bayesian framework. Methods: We searched the Embase, PubMed, Cochrane Central Register of Controlled Trials, Web of Science, Scopus, and ProQuest, for randomized controlled trials published from inception to February 2021 in any languages. The injection therapies included corticosteroids (C...
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BACKGROUND Compared to conventional therapies, biologics are more effective but expensive in treating psoriasis. OBJECTIVE To evaluate the efficacy and cost-efficacy of biologic therapies for psoriasis. METHODS We conducted a meta-analysis to calculate the efficacy of etanercept, adalimumab, infliximab, and ustekinumab for at least 75% reduction in the Psoriasis Area and Severity Index scor...
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Multiple biologic treatments are licensed for psoriasis. The lack of head-to-head randomized controlled trials makes choosing between them difficult for patients, clinicians, and guideline developers. To establish their relative efficacy and tolerability, we searched MEDLINE, PubMed, Embase, and Cochrane for randomized controlled trials of licensed biologic treatments for skin psoriasis. We per...
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Psoriasis is a persistent skin disorder characterised by the hyperproliferation of keratinocytes, with development of scaly erythematous plaques. Progressive basic scientific research has led to a better understanding of the pathophysiology, and now dysregulation of the immune system has been identified to be a crucial event in the disease (Figure 1). Attention focusing on more specific targets...
متن کاملBiologic therapies for moderate to severe psoriasis are not interchangeable.
Health care managers and hospital pharmacists are increasingly compelling prescribers to use medication substitutes. This policy becomes particularly evident when the agents are biologics with shared indications based on their assumed clinical equivalence and efficiency (cost-effectiveness), and in these cases the involvement of clinicians in decision making is often minimal or nonexistent. Lac...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.06.040